If there is one team that has more experience in the Europa League than others, it would have to be Sevilla. The first game, which was played in Prague, ended in a somewhat surprising result of 2:2. Of course, away goals is a great advantage, and Sevilla does not necessarily have to win the game to advance. A draw such as 0:0 or 1:1 would be enough for them.

However, the Spanish club will definitely not focus on defense too much and will look to attack and put this game to bed as soon as possible. The difference in experience between these two teams is definitely there. Sevilla is more than likely to go through here. 

The first game in Frankfurt ended in a goalless draw, which was a bit surprising, to be honest. Inter has a good defensive record at home, and they tend to win more games at the San Siro than lose. Frankfurt is by no means a top-tier German side, so it should be an advantage to Inter.

This game will more than likely end with one goal, and between the two teams, Inter definitely has better odds of scoring. 

One of the most interesting games in the knockout stage for this round. Dinamo has one goal lead which they were able to achieve at home. However, Benfica has been playing good football this season, and home is where they have scored plenty of goals.

A minimal goal advantage is still an advantage, but it might not be enough for the Croatian club to see them go through to the next stage.

After the first game, which ended at 3:1 in favor of Rennes, the French club is the favorite to advance to the next stage. And even though Arsenal are the ones playing at home, they will be missing Sokratis at defense. Rennes has nothing to lose, so it is more than likely that they will be looking to exploit Arsenal's defense, just like the first game.

The Gunners might have had a boost in their confidence after beating Man Utd at home, but this game will be entirely different.

A lot of crazy things are happening this year in the Champions League. Therefore, I am willing to bet that Lyon will be the team to advance to the next round. They do not need to win a game, a draw with some goals will see them through to the next round.

Lyon has shown time and time again that they are more than capable of fighting against top teams this season (Man City being one of the best examples).

This season is unpredictable, so who knows? Lyon is more than capable of pulling this off.

Despite the fact that Atletico are doing great in terms of their defense and have a lead of two goals without conceding, Juventus are the likely of the two to win this particular match. The Italian club has been doing somewhat great in the domestic league, and are playing at home with nothing to lose. Cristiano has still yet to prove himself in the competition this season, and this will be the game for that.

Juve are at home, and Atletico will more than likely go for the defensive approach. Winning the game for Turin is more than possible, but advancing is less likely.

Despite what the bookies are saying, I still believe that United are the favorites to win this game. They have a great recent history against Arsenal, and OGS will have more than enough motivated players after what happened in Paris a few days ago.

Arsenal has lost against Rennes during the midweek, and they will have one less day to prepare. Martial, Matic, and Herrera might possibly feature in this game. Though that is not certain, it should give a boost to United.

The game will turn out depending on which Arsenal shows up. Given how inconsistent they have been, I am willing to go for Manchester win in this one.

Even though Roma has an advantage of one goal after winning the first game 2:1, Porto should be the team to take this one.

First of all, the Portuguese were missing some of their key players due to injuries and suspensions. Moreover, the game is in Porto, which is always an advantage.

Finally, Roma has been quite inconsistent when they are playing away, and against tough opponents.

Despite what is happening this season in Europe, all points are in favor of Porto.

Derby has lost their last four games. However, they were either away or against tough opposition. Wigan, on the other hand, has drawn their last four games, three of which they played at home. This shows that the team is lacking something to close matches.

Given how far apart the two are on the table, and that Derby is playing at home, it should definitely be a win for Derby County. They need to get three points and be back in the top six. 

Even though everyone is expecting a Real Madrid advancement in this tie, I believe that they have a lot of problems internally and do not seem to be doing that hot at the moment. This is a perfect chance for Ajax to expose the opposition and cause a big upset. It is rare to see Real Madrid being in such a weak condition.

If Ajax can show up for this game, then I am fairly certain that they have what it takes to advance to the next stage. 

North London derby is always entertaining to watch. With Harry Kane back in the picture, we can expect more of Tottenham. However, they have struggled in their last two games and lost. Meanwhile, Arsenal has been firing up on all cylinders and are closing in on the third spot on the table.

Nevertheless, the game is not at the Emirates, which should give more boost to Tottenham.

It is rare to see Pochetino's side lose three games in a row. And given how they never draw, all signs are pointing to Tottenham's victory.

Leeds has lost their game against QPR, but the same can be said about Bromwich.

The first game between these two clubs ended in favor of West Brom - 4:1

However, this game should be something different in its entirety. Leeds is the team playing at home, and it is crucial three points to give them more momentum if they want to get promoted.

It will be one of the more interesting games, but I believe that the ones to win this one will be Leeds United.

These type of games are always difficult to call, but looking at how the teams have performed so far in the season, RoPS looks to be doing better, especially looking at the last five games or so.

RoPS are also playing at home, which should be considered quite a bit advantage in this type of game. 

Given that Valencia is the team playing at home and has a better lineup on paper, it should be a no-brainer that they are the favorites to win the game. Even the odds are massively in their favor.

Also, if you compare the form of both teams, Valencia has a clear advantage here. 

Even though Atalanta were the ones to kick Juventus from the competition, I am still going for Fiorentina. They are playing at home, and have a better run of games. Atalanta has lost two of their last games, and it shows that the team is lacking something.

As things in Serie A look to be settled, these two will be sure to put everything into winning the Cup. A tough match awaits here, but Fiorentina is a stronger side on paper, therefore, they should be the ones to get a win. 

Even though the last meeting between these two ended in humiliation for Ajax, the history will definitely not repeat itself. Ajax will look to bounce back from what happened and move on to the next stage.

Amsterdam club has been doing quite well in the Champions League this season, but their main focus will likely be domestic competitions. This is a perfect opportunity to make fans happy, and I am sure that the players know that better than anyone. 

Even though Barca has shown amazing result against Sevilla, it was Messi's one-man show, more or less. Meanwhile, Real has been struggling all season but they seem to have picked themselves up and improved.

The first game ended as a draw in Camp Nou, so Real has the advantage. It will be a perfect opportunity to strike at their opponents and move to the next stage of the competition.

It should be a pretty exciting game, and the home team will likely be the ones to win and advance.

These two teams remain to be an enigma of the season. Both perform either great or end up playing a game that is extremely disappointing.

The home advantage does not seem to mean a lot between these two teams. Tottenham has looked like a better team this season, and it shows in the table.

Chelsea, on the other hand, had a decent game in the League Cup final against City, but the biggest takeaway from that game was Kepa's behavior. Something is not right internally in the Chelsea club, and it shows on the pitch. 

Predicting the outcome for this game is difficult, but I am still going for Tottenham. Kane is back, and he should give plenty of boost. Moreover, it is not like Tottenham to lose two games in a row.

Crystal Palace is a tough team to beat. However, the history between them and United show that the Manchester club has an advantage. Yes, the Red Devils will be missing some key players, but OGS has stated that he plans to field a strong squad regardless of injuries.

It will be one of the tougher games for OGS this season, but the team showed excellent defensive prowess against Liverpool, and United still has enough momentum to get into this match with high expectations. 

At the start of the season, Southampton was one of the teams in the relegation zone. They remain to be in that part of the table, but among the current bottom three, this is the team with the highest chance of climbing up.

A fight against Fulham is somewhat a direct confrontation. Southampton has the perfect opportunity to get three points because, with the way Fulham has been playing, it would be impossible to expect them to not get relegated.

 

This is probably as dead even of a game as it gets. The teams are next to each other on the table, with relatively same form in their recent games. Again, I am going for Sheffield mostly because they are at home and had no losses in their last five games.

It should be an entertaining match, and one to watch if you do not have anything better to do. 

Even though QPR is at home, they have been on a really poor run of games. Meanwhile, Leeds is one of the teams aiming to take the top of the Championship and play in the Premier League next season.

Looking at how both of these two have performed this season, it would not be a stretch to suggest that Leeds should have one of the easier games of the season. I expect the away team to get those three points which should put them closer toward their goals. 

This game is difficult to call because both teams have not had the best of forms recently. Sure, Hull is ten points ahead of Milwall, and are playing at home. These are the main reasons why I am willing to bet on Hull City. Nevertheless, I do not expect an easy win for them, but they should win all the same.

Bristol has been doing quite well in the Championship. Their opponents, on the other hand, have a few slips here and there. It will be one of the more interesting games of the round, but the most likely outcome is Bristol getting those three points and continue their fight for a promotion.

I am going to be a bit bold here and go with Milan for this game. The general consensus seems to be favoring Lazio because they were a bit more stable throughout the season. However, it would seem that Milan has finally found the form that they have been looking for. It would not be a stretch to say that they have quite a lot of momentum at the moment. 

New signings have fired up Gatusso's team, and it would not be that surprising to see them win here.

Both teams seem to be running away from the relegation zone. And looking at their recent games, there is almost no difference in how they have performed.

I am willing to go with Newcastle for this one because they are at home, and have made some new signings who should be settling right about now. The lineup of Newcastle is stronger on paper, too.

This will likely be a tough game, but one where magpies should be getting all three points. 

Everything is in favor of Wolverhampton. The odds, their recent run, and the fact that Huddersfield has been on what look to be one of the worst runs of any team ever. 

Wolverhampton, despite being promoted for the first season, has been doing really well. They are probably the best team behind the big six, and who knows how they will be performing next season.

For this particular game, though, it would be difficult to expect anything but a win for the away side.